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Pathogenic Variants in GALC Gene Correlate With Late Onset Krabbe Disease and Vision Loss: Case Series and Review of Literature

Background: Krabbe disease is an autosomal recessive demyelinating disorder resulting from deficiency of the lysosomal enzyme galactocerebrosidase. While blindness is often described as a characteristic finding of the disease, it is more common in the infantile phenotype, where vision loss typically...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Bascou, Nicholas A., Beltran-Quintero, Maria L., Escolar, Maria L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593573/
https://ncbi.nlm.nih.gov/pubmed/33178108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.563724
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