Long-Term Consequences of High Titer Neutralizing Antibodies to Interferon-β in Multiple Sclerosis

BACKGROUND: Neutralizing anti-drug antibodies (NAbs) to interferon beta (IFNβ) develop in up to 47% of multiple sclerosis (MS) treated patients inhibiting treatment effect of IFNβ. However, the long-term effect of NAbs remain unknown. OBJECTIVE: To investigate the long-term consequences of high tite...

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Опубликовано в: :Front Immunol
Главные авторы: Dunn, Nicky, Fogdell-Hahn, Anna, Hillert, Jan, Spelman, Tim
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593513/
https://ncbi.nlm.nih.gov/pubmed/33178215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.583560
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