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PE homeostasis rebalanced through mitochondria-ER lipid exchange prevents retinal degeneration in Drosophila

The major glycerophospholipid phosphatidylethanolamine (PE) in the nervous system is essential for neural development and function. There are two major PE synthesis pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum (ER) and the phosphatidylserine decarboxylase (PSD) pathway in mito...

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Vydáno v:PLoS Genet
Hlavní autoři: Zhao, Haifang, Wang, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592913/
https://ncbi.nlm.nih.gov/pubmed/33064773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009070
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