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Mild hypoxia triggers transient blood–brain barrier disruption: a fundamental protective role for microglia

We recently demonstrated that when mice are exposed to chronic mild hypoxia (CMH, 8% O(2)), blood vessels in the spinal cord show transient vascular leak that is associated with clustering and activation of microglia around disrupted vessels. Importantly, microglial depletion profoundly increased hy...

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Pubblicato in:Acta Neuropathol Commun
Autori principali: Halder, Sebok K., Milner, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592567/
https://ncbi.nlm.nih.gov/pubmed/33115539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01051-z
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