Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia

BACKGROUND: Hyperhomocysteinemia is a risk factor for ischemic stroke; however, a targeted treatment strategy is lacking partly because of limited understanding of the causal role of homocysteine in cerebrovascular pathogenesis. METHODS AND RESULTS: In a genetic model of cystathionine beta synthase...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Gu, Sean X., Sonkar, Vijay K., Katare, Parmeshwar B., Kumar, Rahul, Kruger, Warren D., Arning, Erland, Bottiglieri, Teodoro, Lentz, Steven R., Dayal, Sanjana
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070222/
https://ncbi.nlm.nih.gov/pubmed/32067580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013368
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