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Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia
BACKGROUND: Hyperhomocysteinemia is a risk factor for ischemic stroke; however, a targeted treatment strategy is lacking partly because of limited understanding of the causal role of homocysteine in cerebrovascular pathogenesis. METHODS AND RESULTS: In a genetic model of cystathionine beta synthase...
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| Veröffentlicht in: | J Am Heart Assoc |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7070222/ https://ncbi.nlm.nih.gov/pubmed/32067580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013368 |
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