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Unaccompanied mechanosensory domain mediates low expression of glycoprotein Ibα: Implications for Bernard-Soulier syndrome
BACKGROUND: Disruption of protein folding or inter-subunit interactions in the platelet glycoprotein (GP)Ib-IX complex leads to its abnormally low expression in the plasma membrane, the hallmark of Bernard-Soulier syndrome (BSS). OBJECTIVE: To discover the molecular mechanism by which GPIbα in the a...
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| Publicado no: | J Thromb Haemost |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7592420/ https://ncbi.nlm.nih.gov/pubmed/31749281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14684 |
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