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Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation
The NLRC4 inflammasome assembles in response to detection of bacterial invasion, and NLRC4 activation leads to the production of IL-1β and IL-18 together with pyroptosis-mediated cell death. Missense activating mutations in NLRC4 cause autoinflammatory disorders whose symptoms are distinctly depende...
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| Yayımlandı: | Front Immunol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7592392/ https://ncbi.nlm.nih.gov/pubmed/33178225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591713 |
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