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An inherited mutation in NLRC4 causes autoinflammation in human and mice
Autoinflammatory syndromes cause sterile inflammation in the absence of any signs of autoimmune responses. Familial cold autoinflammatory syndrome (FCAS) is characterized by intermittent episodes of rash, arthralgia, and fever after exposure to cold stimuli. We have identified a missense mutation in...
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| Publié dans: | J Exp Med |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4235634/ https://ncbi.nlm.nih.gov/pubmed/25385754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141091 |
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