Loss of the Nuclear Protein RTF2 Enhances Influenza Virus Replication

While hundreds of genes are induced by type I interferons, their roles in restricting the influenza virus life cycle remain mostly unknown. Using a loss-of-function CRISPR screen in cells prestimulated with interferon beta (IFN-β), we identified a small number of factors required for restricting inf...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chia, Bing Shao, Li, Bo, Cui, Ang, Eisenhaure, Thomas, Raychowdhury, Raktima, Lieb, David, Hacohen, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592231/
https://ncbi.nlm.nih.gov/pubmed/32878895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00319-20
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