Proteolysis of Von Willebrand Factor Influences Inflammatory Endothelial Activation and Vascular Compliance in Atherosclerosis

This study used in vivo molecular imaging to characterize endotheliall activation attributable to von Willebrand factor (vWF)-mediated platelet adhesion in atherosclerosis. In atherosclerotic mice lacking the low-density lipoprotein receptor on Western diet, the additional genetic deletion of the AD...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Ozawa, Koya, Muller, Matthew A., Varlamov, Oleg, Tavori, Hagai, Packwood, William, Mueller, Paul A., Xie, Aris, Ruggeri, Zaverio, Chung, Dominic, López, José A., Lindner, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Preclinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591934/
https://ncbi.nlm.nih.gov/pubmed/33145464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.08.009
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