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Lysosomal trafficking mediated by Arl8b and BORC promotes invasion of cancer cells that survive radiation

Enhanced invasiveness, a critical determinant of metastasis and poor prognosis, has been observed in cancer cells that survive cancer therapy, including radiotherapy. Here, we show that invasiveness in radiation-surviving cancer cells is associated with alterations in lysosomal exocytosis caused by...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Wu, Ping-Hsiu, Onodera, Yasuhito, Giaccia, Amato J., Le, Quynh-Thu, Shimizu, Shinichi, Shirato, Hiroki, Nam, Jin-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591908/
https://ncbi.nlm.nih.gov/pubmed/33110168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01339-9
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