Transferrin receptor 1 is a cellular receptor for human heme-albumin

Iron is essential for living cells. Uptake of iron-loaded transferrin by the transferrin receptor 1 (CD71, TFR) is a major but not sufficient mechanism and an alternative iron-loaded ligand for CD71 has been assumed. Here, we demonstrate that CD71 utilizes heme-albumin as cargo to transport iron int...

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Publicado no:Commun Biol
Main Authors: Jennifer, Brell, Berg, Verena, Modak, Madhura, Puck, Alexander, Seyerl-Jiresch, Maria, Künig, Sarojinidevi, Zlabinger, Gerhard J., Steinberger, Peter, Chou, Janet, Geha, Raif S., Öhler, Leopold, Yachie, Akihiro, Choe, Hyeryun, Kraller, Markus, Stockinger, Hannes, Stöckl, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591885/
https://ncbi.nlm.nih.gov/pubmed/33110194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01294-5
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