Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis

Interleukin (IL) 35 is a novel immunosuppressive heterodimeric cytokine in IL-12 family. Whether and how IL-35 regulates ischemia-induced angiogenesis in peripheral artery diseases are unrevealed. To fill this important knowledge gap, we used loss-of-function, gain-of-function, omics data analysis,...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Fu, Hangfei, Sun, Yu, Shao, Ying, Saredy, Jason, Cueto, Ramon, Liu, Lu, Drummer, Charles, Johnson, Candice, Xu, Keman, Lu, Yifan, Li, Xinyuan, Meng, Shu, Xue, Eric R., Tan, Judy, Jhala, Nirag C., Yu, Daohai, Zhou, Yan, Bayless, Kayla J., Yu, Jun, Rogers, Thomas J., Hu, Wenhui, Snyder, Nathaniel W., Sun, Jianxin, Qin, Xuebin, Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591706/
https://ncbi.nlm.nih.gov/pubmed/33154757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.595813
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