Silencing of sinusoidal DDR1 reduces murine liver metastasis by colon carcinoma

Liver metastasis depends on the collagenous microenvironment generated by hepatic sinusoidal cells (SCs). DDR1 is an atypical collagen receptor linked to tumor progression, but whether SCs express DDR1 and its implication in liver metastasis remain unknown. Freshly isolated hepatic stellate cells (H...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Romayor, Irene, Badiola, Iker, Benedicto, Aitor, Márquez, Joana, Herrero, Alba, Arteta, Beatriz, Olaso, Elvira
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591579/
https://ncbi.nlm.nih.gov/pubmed/33110221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75395-w
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