Liver sinusoidal endothelial cell ICAM-1 mediated tumor/endothelial crosstalk drives the development of liver metastasis by initiating inflammatory and angiogenic responses

The prometastatic stroma generated through tumor cells/host cells interaction is critical for metastatic growth. To elucidate the role of ICAM-1 on the crosstalk between tumor and primary liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), implicated in tumor adhesion and a...

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Publicado en:Sci Rep
Autores principales: Benedicto, Aitor, Herrero, Alba, Romayor, Irene, Marquez, Joana, Smedsrød, Bård, Olaso, Elvira, Arteta, Beatriz
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739321/
https://ncbi.nlm.nih.gov/pubmed/31511625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49473-7
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