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β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes

Boosting energy expenditure by harnessing the activity of brown adipocytes is a promising strategy for combatting the global epidemic of obesity. Many studies have revealed that the β(3)-adrenergic receptor agonist is a potent activator of brown adipocytes, even in humans, and PKA and p38 MAPK have...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Hattori, Kazuki, Wakatsuki, Hiroaki, Sakauchi, Chihiro, Furutani, Shotaro, Sugawara, Sho, Hatta, Tomohisa, Natsume, Tohru, Ichijo, Hidenori
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591029/
https://ncbi.nlm.nih.gov/pubmed/33108364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232645
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