The mitochondrial protein PGAM5 suppresses energy consumption in brown adipocytes by repressing expression of uncoupling protein 1

Accumulating evidence suggests that brown adipose tissue (BAT) is a potential therapeutic target for managing obesity and related diseases. PGAM family member 5, mitochondrial serine/threonine protein phosphatase (PGAM5), is a protein phosphatase that resides in the mitochondria and regulates many b...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sugawara, Sho, Kanamaru, Yusuke, Sekine, Shiori, Maekawa, Lila, Takahashi, Akinori, Yamamoto, Tadashi, Watanabe, Kengo, Fujisawa, Takao, Hattori, Kazuki, Ichijo, Hidenori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186182/
https://ncbi.nlm.nih.gov/pubmed/32144202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011508
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