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Treating primary immunodeficiencies with defects in NK cells: from stem cell therapy to gene editing

Primary immunodeficiency diseases (PIDs) are rare diseases that are characterized by genetic mutations that damage immunological function, defense, or both. Some of these rare diseases are caused by aberrations in the normal development of natural killer cells (NKs) or affect their lytic synapse. Th...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Eguizabal, C., Herrera, L., Inglés-Ferrándiz, M., Izpisua Belmonte, J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590703/
https://ncbi.nlm.nih.gov/pubmed/33109263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01964-5
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