Expression and Localization of Paneth Cells and Their α-Defensins in the Small Intestine of Adult Mouse

Paneth cells contribute to intestinal innate immunity by sensing bacteria and secreting α-defensin. In Institute of Cancer Research (ICR) mice, α-defensin termed cryptdin (Crp) in Paneth cells consists of six major isoforms, Crp1 to 6. Despite accumulating evidences that α-defensin functions in cont...

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Опубликовано в: :Front Immunol
Главные авторы: Nakamura, Kiminori, Yokoi, Yuki, Fukaya, Rie, Ohira, Shuya, Shinozaki, Ryuga, Nishida, Takuto, Kikuchi, Mani, Ayabe, Tokiyoshi
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590646/
https://ncbi.nlm.nih.gov/pubmed/33154750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.570296
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