Paneth cell α-defensin misfolding correlates with dysbiosis and ileitis in Crohn’s disease model mice

Crohn’s disease (CD) is an intractable inflammatory bowel disease, and dysbiosis, disruption of the intestinal microbiota, is associated with CD pathophysiology. ER stress, disruption of ER homeostasis in Paneth cells of the small intestine, and α-defensin misfolding have been reported in CD patient...

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Detalles Bibliográficos
Publicado en:Life Sci Alliance
Main Authors: Shimizu, Yu, Nakamura, Kiminori, Yoshii, Aki, Yokoi, Yuki, Kikuchi, Mani, Shinozaki, Ryuga, Nakamura, Shunta, Ohira, Shuya, Sugimoto, Rina, Ayabe, Tokiyoshi
Formato: Artigo
Idioma:Inglês
Publicado: Life Science Alliance LLC 2020
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190275/
https://ncbi.nlm.nih.gov/pubmed/32345659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900592
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