Longevity, clonal relationship, and transcriptional program of celiac disease–specific plasma cells

Disease-specific plasma cells (PCs) reactive with transglutaminase 2 (TG2) or deamidated gluten peptides (DGPs) are abundant in celiac disease (CeD) gut lesions. Their contribution toward CeD pathogenesis is unclear. We assessed expression of markers associated with PC longevity in 15 untreated and...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Lindeman, Ida, Zhou, Chunyan, Eggesbø, Linn M., Miao, Zhichao, Polak, Justyna, Lundin, Knut E.A., Jahnsen, Jørgen, Qiao, Shuo-Wang, Iversen, Rasmus, Sollid, Ludvig M.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590513/
https://ncbi.nlm.nih.gov/pubmed/33095260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200852
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