Longevity, clonal relationship, and transcriptional program of celiac disease–specific plasma cells

Disease-specific plasma cells (PCs) reactive with transglutaminase 2 (TG2) or deamidated gluten peptides (DGPs) are abundant in celiac disease (CeD) gut lesions. Their contribution toward CeD pathogenesis is unclear. We assessed expression of markers associated with PC longevity in 15 untreated and...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Lindeman, Ida, Zhou, Chunyan, Eggesbø, Linn M., Miao, Zhichao, Polak, Justyna, Lundin, Knut E.A., Jahnsen, Jørgen, Qiao, Shuo-Wang, Iversen, Rasmus, Sollid, Ludvig M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590513/
https://ncbi.nlm.nih.gov/pubmed/33095260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200852
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