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Tetramer-visualized gluten-specific CD4+ T cells in blood as a potential diagnostic marker for coeliac disease without oral gluten challenge

BACKGROUND: Diagnosing coeliac disease (CD) can be challenging, despite highly specific autoantibodies and typical mucosal changes in the small intestine. The T-cell response to gluten is a hallmark of the disease that has been hitherto unexploited in clinical work-up. OBJECTIVES: We aimed to develo...

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Detalhes bibliográficos
Main Authors: Christophersen, Asbjørn, Ráki, Melinda, Bergseng, Elin, Lundin, Knut EA, Jahnsen, Jørgen, Sollid, Ludvig M, Qiao, Shuo-Wang
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114117/
https://ncbi.nlm.nih.gov/pubmed/25083284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640614540154
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