Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression

BACKGROUND: Immunotherapy has recently been proposed as a promising treatment to stop breast cancer (BrCa) progression and metastasis. However, there has been limited success in the treatment of BrCa with immune checkpoint inhibitors. This implies that BrCa tumors have other mechanisms to escape imm...

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Veröffentlicht in:Breast Cancer Res
Hauptverfasser: Heng, Benjamin, Bilgin, Ayse A., Lovejoy, David B., Tan, Vanessa X., Milioli, Heloisa H., Gluch, Laurence, Bustamante, Sonia, Sabaretnam, Tharani, Moscato, Pablo, Lim, Chai K., Guillemin, Gilles J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590459/
https://ncbi.nlm.nih.gov/pubmed/33109232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01351-1
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