Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression

BACKGROUND: Immunotherapy has recently been proposed as a promising treatment to stop breast cancer (BrCa) progression and metastasis. However, there has been limited success in the treatment of BrCa with immune checkpoint inhibitors. This implies that BrCa tumors have other mechanisms to escape imm...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Heng, Benjamin, Bilgin, Ayse A., Lovejoy, David B., Tan, Vanessa X., Milioli, Heloisa H., Gluch, Laurence, Bustamante, Sonia, Sabaretnam, Tharani, Moscato, Pablo, Lim, Chai K., Guillemin, Gilles J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590459/
https://ncbi.nlm.nih.gov/pubmed/33109232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01351-1
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