The Role of the RANKL/RANK Axis in the Prevention and Treatment of Breast Cancer with Immune Checkpoint Inhibitors and Anti-RANKL

The receptor activator of nuclear factor-κB (RANK) and the RANK ligand (RANKL) were reported in the regulation of osteoclast differentiation/activation and bone homeostasis. Additionally, the RANKL/RANK axis is a significant mediator of progesterone-driven mammary epithelial cell proliferation, pote...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Simatou, Aristofania, Sarantis, Panagiotis, Koustas, Evangelos, Papavassiliou, Athanasios G., Karamouzis, Michalis V.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590202/
https://ncbi.nlm.nih.gov/pubmed/33066388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207570
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