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Inhibition of c‐MET increases the antitumour activity of PARP inhibitors in gastric cancer models

Gastric cancer is the fifth most common malignancy and the third leading cause of cancer‐related death worldwide. Activation of c‐MET increases tumour cell survival through the initiation of the DNA damage repair pathway. PARP is an essential key in the DNA damage repair pathway. The primary role of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Mol Med
Prif Awduron: Koustas, Evangelos, Karamouzis, Michalis V., Sarantis, Panagiotis, Schizas, Dimitrios, Papavassiliou, Athanasios G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521333/
https://ncbi.nlm.nih.gov/pubmed/32686903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15655
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