Allogeneic adipose‐derived stem cells promote ischemic muscle repair by inducing M2 macrophage polarization via the HIF‐1α/IL‐10 pathway

Adipose‐derived mesenchymal stem cells (ASCs) are multipotent stromal cells that possess considerable therapeutic potential for tissue remodeling. However, their protective mechanism in critical limb ischemia has not been fully defined. After the occlusion of blood vessels, hypoxia becomes a promine...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Liu, Junchao, Qiu, Peng, Qin, Jinbao, Wu, Xiaoyu, Wang, Xin, Yang, Xinrui, Li, Bo, Zhang, Wenjie, Ye, Kaichuang, Peng, Zhiyou, Lu, Xinwu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Regenerative Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590195/
https://ncbi.nlm.nih.gov/pubmed/32627897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3250
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