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Glyoxalase‐1 Overexpression Reverses Defective Proangiogenic Function of Diabetic Adipose‐Derived Stem Cells in Streptozotocin‐Induced Diabetic Mice Model of Critical Limb Ischemia

Adipose‐derived stem cell (ADSC)‐based therapy is promising for critical limb ischemia (CLI) treatment, especially in patients with diabetes. However, the therapeutic effects of diabetic ADSCs (D‐ADSCs) are impaired by the diabetes, possibly through intracellular reactive oxygen species (ROS) accumu...

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Detalles Bibliográficos
Publicado en:Stem Cells Transl Med
Main Authors: Peng, Zhiyou, Yang, Xinrui, Qin, Jinbao, Ye, Kaichuang, Wang, Xin, Shi, Huihua, Jiang, Mier, Liu, Xiaobing, Lu, Xinwu
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442730/
https://ncbi.nlm.nih.gov/pubmed/28170200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0380
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