Therapeutic Implications for PDE2 and cGMP/cAMP Mediated Crosstalk in Cardiovascular Diseases

Phosphodiesterases (PDEs) are the principal superfamily of enzymes responsible for degrading the secondary messengers 3′,5′-cyclic nucleotides cAMP and cGMP. Their refined subcellular localization and substrate specificity contribute to finely regulate cAMP/cGMP gradients in various cellular microdo...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Sadek, Mirna S., Cachorro, Eleder, El-Armouche, Ali, Kämmerer, Susanne
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590001/
https://ncbi.nlm.nih.gov/pubmed/33050419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207462
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