Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting

SIMPLE SUMMARY: Well-differentiated/dedifferentiated liposarcomas (WDLPS/DDLPS) are the most frequent soft tissue sarcomas. Despite the hopes raised by some targeted therapies, effective well-tolerated treatments for DDLPS are still lacking. Small-molecule FGFR inhibitors are currently evaluated in...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Dadone-Montaudié, Bérengère, Laroche-Clary, Audrey, Mongis, Aline, Chamorey, Emmanuel, Di Mauro, Ilaria, Chaire, Vanessa, Finetti, Pascal, Schiappa, Renaud, Le Loarer, François, Birtwisle-Peyrottes, Isabelle, Michiels, Jean-François, Bertucci, François, Pedeutour, Florence, Italiano, Antoine, Bianchini, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589658/
https://ncbi.nlm.nih.gov/pubmed/33092134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12103058
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