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Optical Control of GABA(A) Receptors with a Fulgimide‐Based Potentiator
Optogenetic and photopharmacological tools to manipulate neuronal inhibition have limited efficacy and reversibility. We report the design, synthesis, and biological evaluation of Fulgazepam, a fulgimide derivative of benzodiazepine that behaves as a pure potentiator of ionotropic γ‐aminobutyric aci...
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| Publicado en: | Chemistry |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7589408/ https://ncbi.nlm.nih.gov/pubmed/32307732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202000710 |
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