A photoswitchable GABA receptor channel blocker

BACKGROUND AND PURPOSE: Anion‐selective Cys‐loop receptors (GABA and glycine receptors) provide the main inhibitory drive in the CNS. Both types of receptor operate via chloride‐selective ion channels, though with different kinetics, pharmacological profiles, and localization. Disequilibrium in thei...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Maleeva, Galyna, Wutz, Daniel, Rustler, Karin, Nin‐Hill, Alba, Rovira, Carme, Petukhova, Elena, Bautista‐Barrufet, Antoni, Gomila‐Juaneda, Alexandre, Scholze, Petra, Peiretti, Franck, Alfonso‐Prieto, Mercedes, König, Burkhard, Gorostiza, Pau, Bregestovski, Piotr
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609548/
https://ncbi.nlm.nih.gov/pubmed/30981211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14689
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