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Chymase as a Possible Therapeutic Target for Amelioration of Non-Alcoholic Steatohepatitis

The development and progression of non-alcoholic steatohepatitis (NASH) are linked to oxidative stress, inflammation, and fibrosis of the liver. Chymase, a chymotrypsin-like enzyme produced in mast cells, has various enzymatic actions. These actions include activation of angiotensin II, matrix metal...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Takai, Shinji, Jin, Denan
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589185/
https://ncbi.nlm.nih.gov/pubmed/33066113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207543
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