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Mechanism of Albuminuria Reduction by Chymase Inhibition in Diabetic Mice
Chymase has several functions, such as angiotensin II formation, which can promote diabetic kidney disease (DKD). In this study, we evaluated the effect of the chymase inhibitor TY-51469 on DKD in diabetic db/db mice. Diabetic mice were administered TY-51469 (10 mg/kg/day) or placebo for 4 weeks. No...
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| Gepubliceerd in: | Int J Mol Sci |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7589797/ https://ncbi.nlm.nih.gov/pubmed/33050674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207495 |
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