De Novo T790M Mutation in an L858R Epidermal Growth Factor Receptor Mutant-Associated Lung Adenocarcinoma

SIMPLE SUMMARY: Lung adenocarcinomas caused by (L858R) somatic mutation in the epidermal growth factor receptor (EGFR) show good therapeutic response to tyrosine kinase inhibitors. These tumors develop resistance to therapy mainly after acquired T790M mutation. However, whether the T790M mutation oc...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Fujiwara, Takumi, Kobayashi, Tetsu, Yasuma, Taro, D’Alessandro-Gabazza, Corina N., Toda, Masaaki, Fujimoto, Hajime, Fujiwara, Kentaro, Takeshita, Atsuro, Nishihama, Kota, Okano, Tomohito, D’Alessandro, Valeria Fridman, Takei, Yoshiyuki, Hataji, Osamu, Gabazza, Esteban C
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589092/
https://ncbi.nlm.nih.gov/pubmed/33096790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12103074
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