Inhibition of γ‐glutamyltransferase ameliorates ischaemia‐reoxygenation tissue damage in rats with hepatic steatosis

BACKGROUND AND PURPOSE: Hepatic steatosis may be associated with an increased γ‐glutamyltransferase (γ‐GT) levels. Ischaemia‐reoxygenation (IR) injury causes several deleterious effects. We evaluated the protective effects of a selective inhibitor of γ‐GT in experimentally induced IR injury in rats...

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Publicado en:Br J Pharmacol
Autores principales: Kubota, Ryuichi, Hayashi, Nobuhiko, Kinoshita, Kaori, Saito, Takashi, Ozaki, Kazuaki, Ueda, Yoshimichi, Tsuchishima, Mutsumi, Tsutsumi, Mikihiro, George, Joseph
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589019/
https://ncbi.nlm.nih.gov/pubmed/32910829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15258
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