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Base excision repair and its implications to cancer therapy

Base excision repair (BER) has evolved to preserve the integrity of DNA following cellular oxidative stress and in response to exogenous insults. The pathway is a coordinated, sequential process involving 30 proteins or more in which single strand breaks are generated as intermediates during the rep...

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Сохранить в:
Библиографические подробности
Опубликовано в: :Essays Biochem
Главные авторы: Grundy, Gabrielle J., Parsons, Jason L.
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588666/
https://ncbi.nlm.nih.gov/pubmed/32648895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20200013
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