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Base excision repair and its implications to cancer therapy

Base excision repair (BER) has evolved to preserve the integrity of DNA following cellular oxidative stress and in response to exogenous insults. The pathway is a coordinated, sequential process involving 30 proteins or more in which single strand breaks are generated as intermediates during the rep...

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Detalhes bibliográficos
Publicado no:Essays Biochem
Main Authors: Grundy, Gabrielle J., Parsons, Jason L.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588666/
https://ncbi.nlm.nih.gov/pubmed/32648895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20200013
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