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Base excision repair and its implications to cancer therapy
Base excision repair (BER) has evolved to preserve the integrity of DNA following cellular oxidative stress and in response to exogenous insults. The pathway is a coordinated, sequential process involving 30 proteins or more in which single strand breaks are generated as intermediates during the rep...
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| Published in: | Essays Biochem |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Portland Press Ltd.
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7588666/ https://ncbi.nlm.nih.gov/pubmed/32648895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20200013 |
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