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Structural insight into FANCI–FANCD2 monoubiquitination
The Fanconi anemia (FA) pathway coordinates a faithful repair mechanism for DNA damage that blocks DNA replication, such as interstrand cross-links. A key step in the FA pathway is the conjugation of ubiquitin on to FANCD2 and FANCI, which is facilitated by a large E3 ubiquitin ligase complex called...
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| 發表在: | Essays Biochem |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Portland Press Ltd.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7588663/ https://ncbi.nlm.nih.gov/pubmed/32725171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20200001 |
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