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Investigating the optimum size of nanoparticles for their delivery into the brain assisted by focused ultrasound-induced blood–brain barrier opening

The blood–brain barrier (BBB) has hampered the efficiency of nanoparticle delivery into the brain via conventional strategies. The widening of BBB tight junctions via focused ultrasound (FUS) offers a promising approach for enhancing the delivery of nanoparticles into the brain. However, there is cu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ohta, Seiichi, Kikuchi, Emi, Ishijima, Ayumu, Azuma, Takashi, Sakuma, Ichiro, Ito, Taichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588485/
https://ncbi.nlm.nih.gov/pubmed/33106562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75253-9
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