Highly Sensitive Droplet Digital PCR Method for Detection of de novo EGFR T790M Mutation in Patients with Non-Small Cell Lung Cancer

OBJECTIVE: The aim of this study was to investigate the allelic relation between de novo T790M and concomitant sensitizing EGFR mutations in EGFR-TKIs naïve NSCLCs and to explore whether the formalin-fixed and paraffin-embedded (FFPE) materials affect the detection of de novo EGFR T790M mutation. ME...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Wang, Xun, Li, Xiao, Guo, Haifa, Zhu, Lingxiang, Peng, Zhiyong, Wang, Jun, Yang, Fan, Guo, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588301/
https://ncbi.nlm.nih.gov/pubmed/33116639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S267677
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