α-Synuclein modulates tau spreading in mouse brains

α-Synuclein (α-syn) and tau aggregates are the neuropathological hallmarks of Parkinson’s disease (PD) and Alzheimer’s disease (AD), respectively, although both pathologies co-occur in patients with these diseases, suggesting possible crosstalk between them. To elucidate the interactions of patholog...

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Pubblicato in:J Exp Med
Autori principali: Bassil, Fares, Meymand, Emily S., Brown, Hannah J., Xu, Hong, Cox, Timothy O., Pattabhiraman, Shankar, Maghames, Chantal M., Wu, Qihui, Zhang, Bin, Trojanowski, John Q., Lee, Virginia M.-Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588140/
https://ncbi.nlm.nih.gov/pubmed/33091110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192193
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