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Structure of a DNA G-Quadruplex Related to Osteoporosis with a G-A Bulge Forming a Pseudo-loop

Bone remodeling is a fine-tuned process principally regulated by a cascade triggered by interaction of receptor activator of NF-κB (RANK) and RANK ligand (RANKL). Excessive activity of the RANKL gene leads to increased bone resorption and can influence the incidence of osteoporosis. Although much ha...

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Bibliographic Details
Published in:Molecules
Main Authors: Lenarčič Živković, Martina, Rozman, Jan, Plavec, Janez
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588008/
https://ncbi.nlm.nih.gov/pubmed/33096904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204867
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