Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics

In 2020, nearly one-third of new drugs on the global market were synthetic cannabinoids including the drug of abuse N-(1-adamantyl)-1-(5-pentyl)-1H-indazole-3-carboxamide (5F-APINACA, 5F-AKB48). Knowledge of 5F-APINACA metabolism provides a critical mechanistic basis to interpret and predict abuser...

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Udgivet i:Molecules
Main Authors: Pinson, Anna O., Pouncey, Dakota L., Schleiff, Mary A., Fantegrossi, William E., Prather, Paul L., Radominska-Pandya, Anna, Boysen, Gunnar, Miller, Grover P.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587938/
https://ncbi.nlm.nih.gov/pubmed/33092129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204820
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