Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19

SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage in the lungs in the setting of an overzealous immune response whose origin remains unclear. We present a scalable, propagable, personalized, cost-effective adult stem cell-derived human lung organoid model that is complete with...

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發表在:bioRxiv
Main Authors: Tindle, Courtney, Fuller, MacKenzie, Fonseca, Ayden, Taheri, Sahar, Ibeawuchi, Stella-Rita, Beutler, Nathan, Katkar, Gajanan, Claire, Amanraj, Castillo, Vanessa, Hernandez, Moises, Russo, Hana, Duran, Jason, Crotty Alexander, Laura E., Tipps, Ann, Lin, Grace, Thistlethwaite, Patricia A., Chattopadhyay, Ranajoy, Rogers, Thomas F., Sahoo, Debashis, Ghosh, Pradipta, Das, Soumita
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587781/
https://ncbi.nlm.nih.gov/pubmed/33106807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.10.17.344002
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