Development of Optimized Tissue Factor-Targeted Peptide Amphiphile Nanofibers to Slow Non-Compressible Torso Hemorrhage

Non-compressible torso hemorrhage accounts for a significant portion of preventable trauma deaths. We report here on the development of injectable, targeted supramolecular nanotherapeutics based on peptide amphiphile (PA) molecules that are designed to target tissue factor (TF) and, therefore, selec...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Klein, Mia K., Kassam, Hussein Aziz, Lee, Robert H., Bergmeier, Wolfgang, Peters, Erica B., Gillis, David C., Dandurand, Brooke R., Rouan, Jessica R., Karver, Mark R., Struble, Mark D., Clemons, Tristan D., Palmer, Liam C., Gavitt, Brian, Pritts, Timothy A., Tsihlis, Nick D., Stupp, Samuel I., Kibbe, Melina R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587470/
https://ncbi.nlm.nih.gov/pubmed/32469498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b09243
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