Development of Optimized Tissue Factor-Targeted Peptide Amphiphile Nanofibers to Slow Non-Compressible Torso Hemorrhage

Non-compressible torso hemorrhage accounts for a significant portion of preventable trauma deaths. We report here on the development of injectable, targeted supramolecular nanotherapeutics based on peptide amphiphile (PA) molecules that are designed to target tissue factor (TF) and, therefore, selec...

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Vydáno v:ACS Nano
Hlavní autoři: Klein, Mia K., Kassam, Hussein Aziz, Lee, Robert H., Bergmeier, Wolfgang, Peters, Erica B., Gillis, David C., Dandurand, Brooke R., Rouan, Jessica R., Karver, Mark R., Struble, Mark D., Clemons, Tristan D., Palmer, Liam C., Gavitt, Brian, Pritts, Timothy A., Tsihlis, Nick D., Stupp, Samuel I., Kibbe, Melina R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587470/
https://ncbi.nlm.nih.gov/pubmed/32469498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b09243
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