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Synthesis, Molecular Docking, and In Vitro Boron Neutron Capture Therapy Assay of Carboranyl Sinomenine †

In comparison with pristine sinomenine and carborane precursors, the calculations of molecular docking with matrix metalloproteinases (MMPs) and methylcarboranyl-n-butyl sinomenine showed improved interactions. Accordingly, methylcarboranyl-n-butyl sinomenine shows a high potential in the treatment...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Cai, Jianghong, Hosmane, Narayan S., Takagaki, Masao, Zhu, Yinghuai
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587333/
https://ncbi.nlm.nih.gov/pubmed/33066470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204697
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