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Fluorescence intensity and lifetime redox ratios detect metabolic perturbations in T cells

The auto-fluorescent coenzymes reduced nicotinamide dinucleotide (NADH) and oxidized flavin adenine dinucleotide (FAD) allow label-free detection of cellular metabolism. The optical redox ratio, which is traditionally computed as the ratio of NADH and FAD intensities, allows quantification of cell r...

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Detalhes bibliográficos
Publicado no:Biomed Opt Express
Main Authors: Hu, Linghao, Wang, Nianchao, Cardona, Elizabeth, Walsh, Alex J.
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587263/
https://ncbi.nlm.nih.gov/pubmed/33149978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.401935
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