Validated Reversed-Phase Liquid Chromatographic Method with Gradient Elution for Simultaneous Determination of the Antiviral Agents: Sofosbuvir, Ledipasvir, Daclatasvir, and Simeprevir in Their Dosage Forms

A simple, rapid, sensitive, and precise reversed-phase liquid chromatographic method was developed and validated for the simultaneous determination of four direct-acting antivirals, sofosbuvir (SF), ledipasvir (LD), declatasvir (DC), and simeprevir (SM), in their respective pharmaceutical formulatio...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ezzeldin, Essam, Abo-Talib, Nisreen F., Tammam, Marwa H., Asiri, Yousif A., Amr, Abd El-Galil E., Almehizia, Abdulrahman A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587186/
https://ncbi.nlm.nih.gov/pubmed/33050433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204611
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