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2-D chemical structure image-based in silico model to predict agonist activity for androgen receptor

BACKGROUND: Abnormal activation of human nuclear hormone receptors disrupts endocrine systems and thereby affects human health. There have been machine learning-based models to predict androgen receptor agonist activity. However, the models were constructed based on limited numerical features such a...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Yu, Myeong-Sang, Lee, Jingyu, Lee, Yongmin, Na, Dokyun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586653/
https://ncbi.nlm.nih.gov/pubmed/33106158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03588-1
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